Human Hormones

Thyroid-stimulating hormone (TSH), also called thyrotropin, is a hormone found in the human body. It is secreted by the thyrotrope cells in the anterior pituitary gland. TSH is classified as a peptide hormone.
Secretion and Production

TSH is produced in and secreted by the thyrotrope cells in the anterior pituitary gland. It stimulates the thyroid gland to secrete the hormones thyroxine and triiodothyronine. There are two things that cause secretion of TSH. The first is in response to thyrotropin releasing hormone. The second is in response to low levels of thyroxine and triiodothyronine in the blood.
Pharmacological Uses

Synthetic TSH is commonly administered to patients with thyroid cancer in order to suppress the activity of their thyroid until the cancer is removed by chemotherapy. This prevents the spread of cancer throughout the body.

Thrombopoietin (TPO) is a hormone found in the human body. It is produced in and secreted from the kidneys, liver, striated muscle, and stromal cells in bone marrow. It works to stimulate the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.

Though there are potentially many positive effects of a synthetic thrombopoietin, a safe form of this hormone has not been created. The first recombinant thrombopoietin developed was ineffective, so the research to create synthetic TPO continues. Potential uses include the procurement of platelets for donation, and the recovery of platelet counts after myleosuppressive chemotherapy.