Human Hormones

Thromboxane is a member of the family of lipids known as eicosanoids. It is produced in platelets by thromboxane synthetase.
Secretion and Production

Thromboxane is produced in platelets by thromboxane synthetase, which is produced from the endoperoxides by the cyclooxygenase enzyme from arachidonic acid.
Thromboxane is a vasoconstrictor and a potent hypertensive agent, and it facilitates the clumping of platelets. It is in homeostatic balance in the circulatory system with prostacyclin. The widely used drug aspirin acts by inhibiting the ability of the cyclooxygenase enzyme to synthesize the precursors of thromboxane within platelets.

Pharmacological Uses

Currently, there is no form of synthetic thromboxane on the market for human use.